Cloning referred to a biotechnological process used to create exact copies of DNA fragments, cells, or entire organisms like humans. A being created in such a process was called a clone.

During Earth's Final War, the Asian Confederacy employed cloning farms to create its genetically enhanced super soldiers. The soldiers eventually turned on their creators in the Beijing Coup in order to gain control of these farms. (CS3)

Albrecht Detweiler, Chairman of Manpower Incorporated and de-facto ruler of Mesa, had at least six "sons" who were actually clones of himself, while he was himself a "genetically improved" clone of Mesa's founder, Leonard Detweiler. (SI2)

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